Neurochemical Imbalance Linked with Susceptibility to PTSD

New research finds that an imbalance between two neurochemical systems in the brain is linked to posttraumatic stress disorder with the greater the imbalance, the more serious the symptoms.

Researchers from Uppsala University and the medical university Karolinska Institutet in Stockholm, Sweden, found that people with posttraumatic stress disorder have an imbalance between two neurochemical systems in the brain, serotonin, and substance P.

Experiencing a traumatic event is not uncommon be it a robbery, warfare, a serious car accident, or a sexual assault. Approximately 10 percent of people subjected to trauma suffer long-lasting symptoms in the form of disturbing flashbacks, insomnia, hyperarousal, and anxiety.

If these problems lead to impairment, the person is said to suffer from posttraumatic stress disorder, PTSD.

Prior research has shown that people with PTSD have altered brain anatomy and function. In the new study, researchers discovered people with PTSD have an imbalance between two neurochemical signalling systems of the brain, serotonin, and substance P.

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